The basic biological process called alternative splicing proves vital in making sure important muscle cell proteins switch from their fetal forms to their adult forms. Not doing so could lead to muscle defects and disorders.
Jason Katz, MD, MHS, medical director of UNC’s cardiac intensive care unit, examines the challenges facing cardiac intensive care units and clinicians, and offers innovative recommendations for training, staffing and research for this emerging field.
For the first time, a large clinical trial showed across-the-board cardiovascular benefit of a diabetes drug – liraglutide – a much-needed outcome for people with type 2 diabetes.
UNC’s Alan Hinderliter, MD, teamed up with Duke doctors to quantify the benefit of stress management to heart health.
UNC School of Medicine scientists overcame a significant barrier to convert scar-making fibroblasts into living, beating cardiomyocytes.
Led by scientists at the UNC School of Medicine, the five-year multi-lab effort lays the groundwork for developing treatments.
UNC’s Center for Heart & Vascular Care has been offering Transcatheter Aortic Valve Replacement (TAVR) for less than a year. In that time, the team has built a national reputation for excellence, allowing UNC to be among the first phase of the rollout of a next generation TAVR device, Evolut-R, developed by Medtronic. This valve is the first repositionable transcatheter valve ever available.
In the recent U.S. News and World Report rankings of America’s Best Hospitals, UNC Hospitals was nationally ranked in five of the 16 specialties. In this series, we profile these specialties to learn more about what makes them so outstanding.
The finding published in PLoS One suggests that elevated oxidized LDL cholesterol and fructosamine – a measure of glycated proteins in blood sugar – are signposts for the development of severe coronary disease, especially in females.
UNC’s Heart Health Now! Advancing Heart Health in NC Primary Care project is one of seven grantees awarded as part of the AHRQ initiative, EvidenceNOW – Advancing Heart Health in Primary Care.
The findings could lead to more personalized approaches to controlling platelet activity during heart attacks and other vascular emergencies and diseases. Wolfgang Bergmeier, PhD, professor of biochemistry and biophysics, member of the McAllister Heart Institute at UNC, is senior author of the paper.
By bumping up the levels of a well-known protein in the heart, UNC researchers have found a new way to generate more blood vessels following a heart attack.
