UNC Health Care

Category: Oncology

Joel Tepper

May 29, 2013

The value of randomized clinical trials in radiation oncology clini...

Are there enough clinical trials data to guide every radiation oncology decision in a cancer patient's care? Not necessarily, according to a UNC School of Medicine study.

Cancer, Clinical Trials, Oncology, Research

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Angiosarcoma cells treated with a monoclonal antibody targeting SFRP2 (right) show a significant reduction compared to an untreated control (left).

April 19, 2013

Novel monoclonal antibody inhibits tumor growth in breast cancer an...

The antibody, created at the University of North Carolina, is the first therapeutic discovered that targets a protein known as SFRP2.

Breast Cancer, Oncology, Research, Treatment

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Dot-like invadopodia assemble into circular groups known as “rosettes” inside cancer-associated fibroblasts (CAFs) grown from a human pancreas tumor.  CAFs utilize palladin-containing invadopodia to help the cancer cells move across tissue boundaries.

March 25, 2013

Storming the gates: UNC research probes how pancreatic cancers meta...

Researchers in the lab of Carol Otey, PhD, found that the protein palladin enhances the ability of cancer-associated fibroblasts (CAFs) to assemble organelles known as invadopodia to break down the barriers between cells and create pathways for tumors to spread throughout the body.

Cancer, Oncology, Research

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Christian Jobin

August 17, 2012

UNC-led research links E.coli strain to cancer

The study was led by Christian Jobin, PhD, associate professor in the Division of Gastroenterology and Hepatology in the University of North Carolina School of Medicine.

Cancer, Innovation, Oncology, Research

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Stefanie Sarantopoulos

August 16, 2012

B Cell survival holds key to chronic graft vs. host disease

A team from UNC Lineberger Comprehensive Cancer Center, shows in the laboratory that B cells from patients with chronic GVHD are much more active than cells from patients without the disease.

Cancer, Chronic Illness, Oncology, Research, Treatment

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Jenny Ting

August 6, 2012

UNC team describes novel inflammatory protein function

A UNC-led team of scientists describes the function of a previously uncharacterized protein that dramatically influences inflammation.

Innovation, Oncology, Research

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UNC Chapel

May 10, 2012

UNC Bone Marrow and Stem Cell Transplantation Program achieves outs...

UNC Cancer Care’s Bone Marrow and Stem Cell Transplantation Program is one of only 14 out of 156 centers across the country to be rated an “overperforming” center.

Cancer, Innovation, Oncology, Transplants, Treatment

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Andrew Z. Wang

May 2, 2012

UNC study shows potential to revive abandoned cancer drug by nanopa...

A team of UNC researchers developed nanoparticle carriers to successfully deliver therapeutic doses of a cancer drug that had previously failed clinical development due to pharmacologic challenges.

Cancer, Innovation, Oncology, Studies, Technology, Treatment

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Wenbin Lin

September 20, 2011

UNC scientist proves potential of new nanoparticle design for cance...

A new type of nanoparticle developed in the laboratories at the University of North Carolina has shown potential for more effective delivery of chemotherapy to treat cancer.

Cancer, Genetics, Oncology, Technology, Treatment

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Patients in a hospital.

May 23, 2011

UNC study examines NC cancer patient emergency department visits

The UNC team used a statewide database to collect information on over 35,000 Emergency department (ED) visits. They learned that the top three problems that brought patients to the ED were related to pain, respiratory distress, and gastrointestinal issues (mostly nausea and vomiting).

Cancer, Oncology, Studies

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