UNC Health Care

Category: Research

A woman itching her arm.

March 27, 2017

UNC researchers link orphan receptor to opioid-induced itching

With a more accurate understanding of the characteristics and function of the receptor MRGRPX2, University of North Carolina School of Medicine researchers were also able to create chemical probe that will allow them study the receptor more precisely.

Neurology, Research, Substance Abuse

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Pregnant woman

March 23, 2017

Preterm births more common in mothers who are cancer survivors

UNC Lineberger's Hazel Nichols, PhD, Chelsea Anderson, MPH, and their colleagues report that women diagnosed and treated for cancer during their childbearing years more commonly gave birth prematurely, and to babies whose weights were below normal. Cancer survivors also had a slightly higher rate of cesarean section deliveries.

Cancer, Pregnancy, Research

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Electron microscopy of large

March 23, 2017

The Mechanism of Mucus: UNC discovery could lead to better cystic f...

University of North Carolina scientists found that mucin proteins, which make mucus thick and sticky, fail to unfold properly in the airways of people with cystic fibrosis. And they found the lack of water in the lung can trigger the misfolding mucins.

Gastroenterology, Genetics, Research

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An illustration of bacteria in a person's digestive tract.

March 13, 2017

‘Good’ bacteria is possible solution for unchecked infl...

In a study published in journal Nature Immunology, researchers led by UNC Lineberger member Jenny P.Y. Ting, PhD, describe how inflammation can go unchecked in the absence of a certain inflammation inhibitor called NLRP12. In a harmful feedback loop, this inflammation can upset the balance of bacteria living in the gut. Beneficial bacterial may be the key to reversing inflammation in the absence of this key regulator.

Gastroenterology, Research

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An illustration of a liver with gears.

February 28, 2017

UNC research helps answer why genetic mutation leads to decreased t...

Doctoral student Cassandra Hayne, working with Saskia Naher, PhD, found that a specific mutated version of a lipoprotein binds more effectively to liver cells, thus explaining decreased levels of triglycerides in blood.

Genetics, Hematology, Research

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A woman's reproductive organs represented with flowers.

February 23, 2017

UNC researcher finds safer, less-invasive method of staging endomet...

Using dye to map cancer metastases, Emma Rossi, MD, and UNC collaborators lead large study to help patients avoid complications from surgery.

Cancer, Innovation, Research

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Man thinking with drawing of muscles behind him.

February 23, 2017

Measuring patients’ muscles to predict chemotherapy side effects

UNC Lineberger researchers Hy Muss, MD, Shlomit Strulov Shachar, MD, and colleagues report in the journal Clinical Cancer Research that a measure of muscle mass and muscle quality developed at UNC could potentially help doctors better identify patients at high risk for side effects that could require hospitalization.

Cancer, Research

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February 23, 2017

Autism study gains national attention

Published last week in the journal Nature, the research shows it is possible to use MRIs to predict which high-risk babies will go on to develop autism as toddlers.

Autism, Research, Studies

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A person's hand being checked for blood sugar levels.

February 21, 2017

Researchers implicate suspect in heart disease linked to diabetes

In their study of the IRS-1 protein, researchers at the University of North Carolina found a new lead for reversing or preventing heart disease associated with diabetes.

Cardiology, Diabetes, Research, Vascular Health

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Illustration of a MRI machine.

February 15, 2017

Researchers use MRIs to predict which high-risk babies will develop...

This first-of-its-kind study used MRIs to image the brains of infants, and then researchers used brain measurements and a computer algorithm to accurately predict autism before symptoms set in.

Autism, Research, Technology

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Chris Selby

February 7, 2017

How Life Survives: UNC researchers confirm basic mechanism of DNA r...

Findings come from an advanced DNA sequencing application developed by the lab of University of North Carolina Nobel Laureate Aziz Sancar.

Genetics, Research, Studies

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Robert Tarran

February 6, 2017

UNC researchers find new potential route to treat asthma

Scientists at the UNC School of Medicine have identified and isolated a protein that could play a vital role in regulating proper airway function. When that protein is low in volume or missing altogether, it can cause airway hyper-reactivity in asthma.

Asthma, Research

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