UNC Health Care

Tag: Biochemistry and Biophysics

July 6, 2015

UNC researchers find two biomarkers linked to severe heart disease

The finding published in PLoS One suggests that elevated oxidized LDL cholesterol and fructosamine – a measure of glycated proteins in blood sugar – are signposts for the development of severe coronary disease, especially in females.

Cardiology, Genetics

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Richard Wolfenden

June 1, 2015

New evidence emerges on the origins of life on Earth

University of North Carolina researchers provide evidence for how the genetic code developed in two distinct stages to help primordial chemicals evolve into cells.

Genetics, Research

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Aziz Sancar

May 1, 2015

UNC researchers create DNA repair map of the entire human genome

The new experimental assay can help scientists find the precise locations of repair of DNA damage caused by UV radiation and common chemotherapies. The invention could lead to better cancer drugs or improvements in the potency of existing ones.

Genetics, Research

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Ron Swanstrom

March 18, 2015

Researchers identify timeline for HIV replication in the brain

A new study in PLoS Pathogens shows that HIV can infect the brain early on and should be combated as soon as possible with antiretroviral therapy to limit risk of dementia

HIV/AIDS, Research

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Wolfgang Bergmeier

February 23, 2015

Scientists find a key protein that allows Plavix to conquer platelets

The findings could lead to more personalized approaches to controlling platelet activity during heart attacks and other vascular emergencies and diseases. Wolfgang Bergmeier, PhD, professor of biochemistry and biophysics, member of the McAllister Heart Institute at UNC, is senior author of the paper.

Cardiology, Studies, Vascular Health

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Robert Duronio

February 9, 2015

Epigenetic Breakthrough: A first of its kind tool to study the hist...

Scientists from UNC-Chapel Hill have created a new way to investigate epigenetic mechanisms important in diseases ranging from Alzheimer’s to cancers.

Genetics, Research, Technology

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September 18, 2014

UNC researchers link gene to increased dendritic spines – a signpos...

By deleting the NrCAM gene, scientists have found a potential way to cut back on the neural connections implicated in Autism Spectrum Disorder.

Autism, Genetics, Research

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Aziz Sancar

September 15, 2014

UNC researchers find final pieces to the circadian clock puzzle

Sixteen years after scientists found the genes that control the circadian clock in all cells, the lab of UNC’s Aziz Sancar, MD, PhD, discovered the mechanisms responsible for keeping the clock in sync.

Innovation, Research, Sleep

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Brian Strahl

June 9, 2014

UNC researchers pinpoint new role for enzyme in DNA repair, kidney ...

The discovery, from the lab of Brian Strahl, PhD, offers insights for the creation of better, more targeted therapies for various forms of cancer.

Cancer, Genetics, Research

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Shawn Ahmed

April 24, 2014

UNC researchers link aging to cellular interactions that occur acro...

Shawn Ahmed, PhD, shows that tweaking specific cellular mechanisms helps tiny worms overcome infertility through a pathway of cellular interactions that result in long life. The finding gives clues to how the molecular interactions in cells of one organism affect progeny many generations later.

Cell Biology, Genetics, Research

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UNC Chapel

March 20, 2014

UNC scientists reveal how cells destroy RNA, a key to understanding...

The finding, from the lab of William Marzluff, PhD, provides insight into how genetic diseases, such as various cancers, develop in the body.

Genetics, Research

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Qi Zhang

January 9, 2014

A powerful technique to further understanding of RNA

Qi Zhang sees himself as a warrior. In his lab at the University of North Carolina at Chapel Hill, he wages war on genetic diseases such as cancer and heart disease on a battlefield measured with single atoms.

Genetics, Research

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