UNC researchers find genetic trigger for RSV-induced infant hospita...
The discovery could lead to new therapies and better diagnostics, resulting in fewer hospitalizations of children with respiratory syncytial virus, the leading cause of severe lung infection in babies.
UNC researchers discover new target for dengue virus vaccine
By re-engineering a tiny chain of amino acids in one type of dengue virus, Ralph Baric and Aravinda de Silva discover a new path toward solving the dengue vaccine dilemma. The research has the potential to transform vaccine development for other diseases, including SARS and HIV.
Corbett continues quest for dengue fever vaccine
In this new series, we profile graduate students who conduct research in labs across the UNC School of Medicine. First up is Kizzmekia Corbett, who received an off-campus dissertation fellowship from the UNC Graduate School to travel to Sri Lanka. Corbett will collect blood samples to search for a specific antibody response to the dengue virus, a key step in creating a vaccine for the world's most widespread mosquito-borne disease.
UNC researchers discover gene that suppresses herpes viruses
A research team led by Blossom Damania, PhD, found that suppressing the TLK enzyme causes the activation of the lytic cycle of both EBV and KSHV. During this active phase, these viruses begin to spread and replicate, and become vulnerable to anti-viral treatments.
Immune cell suicide alarm helps destroy escaping bacteria
A University of North Carolina School of Medicine study may have implications for thwarting the effects of bioterrorism attack with lethal microbes, as well as finding a way to save people in septic shock, an overwhelming bacterial infection of the blood.
Antibodies reverse Type 1 diabetes in new immunotherapy study
Scientists at the University of North Carolina School of Medicine have used injections of antibodies to rapidly reverse the onset of Type I diabetes in mice genetically bred to develop the disease.