
Building a Better Opioid
Opioid crisis no more? It may be possible one day thanks to new research from the University of North Carolina School of Medicine.
Addiction, Innovation, Pain, Pharmacology, Physicians, Research
Opioid crisis no more? It may be possible one day thanks to new research from the University of North Carolina School of Medicine.
Addiction, Innovation, Pain, Pharmacology, Physicians, Research
The National Institutes of Health has awarded four UNC experts a translational program project grant (tPPG) to develop and test therapeutics aimed at reducing the hyper-concentration of mucus often found in cystic fibrosis and asthma patients.
Asthma, Cystic Fibrosis, Grants, Innovation, News, Pulmonology
Findings reveal a second target for cure research. Jenny Honeycutt, PhD, a postdoctoral research associate in the division of infectious diseases, is the study's lead author.
The early-stage cellular immunotherapy trials are for patients with either Hodgkin lymphoma or non-Hodgkin lymphoma, who lack other treatment options or are at high risk of their disease returning.
Using dye to map cancer metastases, Emma Rossi, MD, and UNC collaborators lead large study to help patients avoid complications from surgery.
A study at the University of North Carolina found that gene deletion poses a threat to Malaria eradication efforts.
The longitudinal patient-centered AURORA study – the largest study of its kind – will trace the development of posttraumatic stress, minor traumatic brain injury symptoms, chronic pain, and depression, to create new diagnostic tools and treatment interventions.
Variants of the human version of the gene may help explain why people differ so much in their ability to survive artery blockages.
A research question posed through the Crohn’s & Colitis Foundation of America (CCFA) Partners Patient-Powered Research Network CCFA Partners – a collaboration between UNC and the CCFA – served as motivation for this study concept.
In the journal Cell Reports, UNC Lineberger researchers reported they found markedly low levels of the protein NLRX1 in multiple laboratory models of colorectal cancer, and in samples of human tissue. Studies have shown that the protein is known to be involved in regulating immune system signals in order to prevent hyperactive inflammatory responses by the immune system, but UNC Lineberger researchers believe their finding also points to a role for the protein in preventing colorectal cancer growth. Based on their findings, they believe they’ve identified a potential treatment for colorectal cancer with low NLRX1.
In February, UNC neurologist Hae Won Shin, MD, and neurosurgeon Eldad Hadar, MD, were the first in the state to implant the NeuroPace RNS System following the medical device’s recent FDA approval. In clinical trials, the NeuroPace system greatly reduced the number of seizures experienced by patients with severe epilepsy.
UNC School of Medicine and NC State researchers create 3D-printed models of temporal bones to be used for surgical simulation in pediatric cases and for patients with unusual anatomy.