Tag: Cancer
Study confirms link between alcohol consumption, breast cancer risk...
In findings published in the journal Cancer, Epidemiology, Biomarkers & Prevention, UNC Lineberger Comprehensive Cancer Center researchers confirmed the link between alcohol consumption and breast cancer risk in a study in black women. The association has been seen in other studies drawn from majority white populations.
Adventure in the Face of Cancer
At 28 years old, Dave Carbonell was months away from completing his residency in Emergency Medicine at UNC. Then cancer struck—acute lymphoblastic leukemia. Today, after years of intense treatment, he’s cancer free, working as an Emergency Department physician in California and helping other young
‘Good’ bacteria is possible solution for unchecked infl...
In a study published in journal Nature Immunology, researchers led by UNC Lineberger member Jenny P.Y. Ting, PhD, describe how inflammation can go unchecked in the absence of a certain inflammation inhibitor called NLRP12. In a harmful feedback loop, this inflammation can upset the balance of bacteria living in the gut. Beneficial bacterial may be the key to reversing inflammation in the absence of this key regulator.
UNC Lineberger launches innovative cellular immunotherapy program
The early-stage cellular immunotherapy trials are for patients with either Hodgkin lymphoma or non-Hodgkin lymphoma, who lack other treatment options or are at high risk of their disease returning.
UNC researcher finds safer, less-invasive method of staging endomet...
Using dye to map cancer metastases, Emma Rossi, MD, and UNC collaborators lead large study to help patients avoid complications from surgery.
Measuring patients’ muscles to predict chemotherapy side effects
UNC Lineberger researchers Hy Muss, MD, Shlomit Strulov Shachar, MD, and colleagues report in the journal Clinical Cancer Research that a measure of muscle mass and muscle quality developed at UNC could potentially help doctors better identify patients at high risk for side effects that could require hospitalization.
U.S. cancer death rate declines, but work is needed to address loca...
UNC Lineberger researchers Ethan Basch, MD, MSc, and Stephanie Wheeler, PhD, MPH, called for tailored, local-level cancer prevention, screening and treatment efforts to address regional disparities in cancer mortality rates in an editorial published in JAMA on Tuesday.
Cost, technology issues are barriers to real-time cancer patient sy...
In a perspective published in the New England Journal of Medicine, Ethan Basch, MD, MSc, professor of medicine and director of UNC Lineberger’s Cancer Outcomes Research Program, addressed the need for – and the barriers preventing – electronic reporting of patients’ symptoms between visits.
For invasive breast cancer, researchers identify biomarkers of trea...
UNC Lineberger researchers reported at the San Antonio Breast Cancer Symposium they have identified biomarkers they believe can be used as part of a larger model to predict how patients with HER2-positive operative breast cancer will respond to the targeted treatment trastuzumab, commercially known as Herceptin, and chemotherapy.
Brain metastasis persists despite improved targeted treatment for H...
At this year's San Antonio Breast Cancer Symposium, UNC Lineberger researchers and collaborators shared the outcomes of their investigation into the incidence of brain metastasis after a series of drugs were approved to treat HER2-positive metastatic breast cancer, starting with trastuzumab, also known as Herceptin, in the United States in 1998.