UNC Health Care

Tag: Pharmacology

Center: a molecule of LSD bound to a larger serotonin receptor. The lid" that keeps LSD bound so long is the orange bar running through the center."

January 26, 2017

This is LSD attached to a brain cell serotonin receptor

For the first time, UNC School of Medicine researchers crystalized the structure of LSD attached to a human serotonin receptor of a brain cell, and they may have discovered why an “acid trip” lasts so long.

Neurology, Research, Substance Abuse

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Zhen Gu

January 23, 2017

On target: UNC researcher arms platelets to deliver cancer immunoth...

UNC, NCSU biomedical engineering research team’s findings show that engineered platelets can deliver antibodies to kill cancer cells before they can grow or spread elsewhere in the body.

Cancer, Hematology, Research

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John Sondek

December 21, 2016

Inside the world of cell signaling: a G-protein breakthrough

UNC scientists led by John Sondek, PhD, created a new biochemical tool to block specific types of downstream G-protein signaling, opening new avenues of research and potential drug design and discovery.

Gastroenterology, Studies

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Bryan Roth

September 15, 2016

Researchers build a better opioid painkiller from scratch

The new compound could reduce overdoses and possibly curb addiction, while addressing the needs of millions of people suffering with chronic pain.

Research, Treatment

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Illustration of a man on a blue background with colorful pills falling into his open head.

August 24, 2016

How do antidepressants trigger fear and anxiety?

UNC School of Medicine researchers map the anxiety circuit in the brain and use a compound to limit fearful behavior – an acute side effect of commonly prescribed SSRI antidepressants.

Mental Health, Research

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A Zika virus particle (Illustration by David Goodwill)

June 9, 2016

UNC researchers awarded pilot grants for Zika research

UNC investigators will study diagnostics, transmission, and neurological effects of Zika, which has been reported in 62 countries and territories.

Awards, Contagions, Research

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Jonathan Schisler

April 5, 2016

New clues in the quest to prevent clogged arteries

UNC School of Medicine researchers have found a protein that appears to protect against coronary artery disease in older people with surprisingly clear arteries.

Studies, Vascular Health

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Thomas Kash

March 17, 2016

UNC researchers uncover how kappa opioid receptors drive anxiety

Study could lead to new drug development targets for forms of anxiety that are more pathological, such as those associated with excessive alcohol intake or opiate abuse.

Mental Health, Neurology, Research

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Fulton Crews

November 18, 2015

UNC and NCCU awarded $7.5 million for alcohol health disparities re...

This funding will continue a research program investigating the molecular mechanisms of fetal alcohol pathology, alcoholic liver disease, alcohol-related cancers, including breast cancer, and the effects of alcohol and marijuana on brain stem cells and neurotoxicity.

Awards

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Janet Rubin

November 12, 2015

UNC researchers find new way to force stem cells to become bone cells

Potential therapies based on this discovery could help people heal bone injuries or set hardware, such as replacement knees and hips.

Genetics, Research, Treatment

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Bryan Roth

November 9, 2015

Researchers shed pharmacological light on “dark” cellular receptors

UNC and UCSF labs create a new research tool to find homes for two orphan cell-surface receptors, a crucial step toward finding better therapeutics and causes of drug side effects.

Genetics, Research

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